The majority of gallbladder diseases are caused by inflammation due to irritation to the gallbladder wall. This occurs when gallstones obstruct the ducts leading to the small intestine and may eventually lead to necrosis or gangrene. Your gallbladder’s main function is to store the bile produced in your liver and pass it along to the small intestine. Non-alcoholic fatty liver disease (NAFLD) describes a range of conditions caused by a build-up of fat within liver cells. Are these two linked in poor health? You bet! Is anyone looking at this association – not many!